The NEC Society Research Collaborative strives to improve the prevention and treatment of neonatal necrotizing enterocolitis by bringing together multidisciplinary investigators to conduct novel research as one collective team. Click here to learn more about the Research Collaborative.

Active Projects:

• Probiotics QI Project

This Probiotic QI Project will help us to better understand outcomes for babies who receive probiotics as part of their care in the NICU. Participating units that choose to use probiotics will measure babies’ growth and share that data with us. The collective data will then be analyzed to determine if babies who received probiotics have different outcomes than those who did not. The NEC Society engaged in discussions with the FDA to ensure this QI project aligned with their regulatory framework. This project was developed directly from the 2017 NEC Symposium and is now enrolling centers.

• NEC Biorepository

The effort to build the NEC biorepository began at the 2017 NEC Symposium. Participating centers from the Research Collaborative collect and share biological samples from infants affected by NEC, as well as infants who did not experience NEC. The goal is to develop biomarkers to predict a baby’s risk of contracting the disease and offer preventive strategies against it.

• National Benchmarking Tool for NICUs

The goal of this benchmarking database is to collect center-specific data and patient-specific data as a way to analyze the variation of care and compliance to protocols. The Research Collaborative hopes to use this information to develop recommended standards of care. The framework for this project has been developed and the Collaborative will soon start to collect data. 

• Comparative Effectiveness Research with Families in the NICU

Currently, most research within NICUs requires parents to “opt-in” to participate. This project explores an “opt-out” research model, where de-identified data would be available for researchers to use unless parents opt-out. We want to understand the ethical and practical implications of this model where families passively agree to participate in research. The vision is to create a model where critical research needs can be addressed efficiently and with compassion for the trauma that families in the NICU experience.

Support the NEC Society Research Collaborative

Resulting from the 2017 NEC Symposium’s success, the NEC Society Research Collaborative has grown to include nearly 50 investigators from around the world, including many of the United States’ largest pediatric centers. The Research Collaborative strives to improve the prevention and treatment of necrotizing enterocolitis by bringing together multidisciplinary investigators to conduct novel research as one collective team. The Research Collaborative utilizes the patient-family voice in the development, implementation, and analysis of its projects. Thank you for supporting this work!

$50.00

NEC Society Research Collaborative Members

• Steven Abrams, MD, University of Texas at Austin
• Pierro Augustino, MD, University of Toronto 
• Gail E. Besner, MD, Nationwide Children’s Hospital
• Martin Blakely, MD, MS, Vanderbilt University
• Jennifer Canvasser, MSW, NEC Society 
• Michael Caplan, MD, Northshore University Health System
• Elizabeth Cristofalo, MD, MPH, Johns Hopkins Hospital
• Cynthia Downard, MD, MMSc, FACS, University of Louisville
• Henri Ford, MD, University of Southern California 
• Samir K. Gadepalli, MD, MBA, University of Michigan
• Parvesh Garg, University of Mississippi Medical Center
• Christopher Gayer, MD, PhD, Children’s Hospital Los Angeles
• Sheila M. Gephart, PhD, RN, University of Arizona
• Katherine Gregory, PhD, Brigham and Women’s Hospital
• Misty Good, MD, MS, Washington University School of Medicine
• David J. Hackam,MD, PhD, FACS, Johns Hopkins Hospital
• Amy Hair, MD, Baylor College of Medicine, Texas Children’s Hospital
• Catherine J. Hunter, MD, Children’s Hospital of Chicago  
• Minesh Khashu, M.D., NHS
• Ulf Kessler, Service de Chirurgie, HFR Fribourg
• Jae Kim, MD, PhD, University of California, San Diego
• Liza Konnikova, MD, PhD, Harvard Medical School
• Troy A. Markel, MD, FACS, FAAP, Indiana University
• Camilia R. Martin, MD, MS, Beth Israel Deaconess Medical Center-Harvard Medical School
• Colin Martin, MD, University of Alabama at Birmingham
• Steven J. McElroy, MD, University of Iowa
• R. Lawrence Moss, MD, Nationwide Children’s Hospital
• Josef Neu, MD, University of Florida Professor of Pediatrics
• Oluyinka Olutoye, MD, PhD, Baylor College of Medicine 
• Mohan Pammi, M.D., Ph.D., Baylor College of Medicine
• Aloka L. Patel, M.D., Rush University Children’s Hospital
• Ravi Mangal Patel, M.D., Emory University School of Medicine and Children’s Healthcare of Atlanta
• Alexander Penn, PhD, US Army Institute of Surgical Research
• Muralidhar H. Premkumar, MD, MRCPCH, MS, Baylor College of Medicine
• Brian Scottoline, Oregon Health & Science University
• Karl Sylvester, MD, Stanford
• Erin Umberger, M.Arch, NEC Society  
• Mark Underwood, MD, University of California, Davis
• Brad W. Warner, MD, Washington University 
• Joern-Hendrik Weitkamp, Vanderbilt University
• Scott Welak, M.D., Medical College of Wisconsin
• Toby Debra Yanowitz, MD, MS, University of Pittsburgh School of Medicine