The NEC Society is a 501(c)(3) nonprofit organization committed to building a world without necrotizing enterocolitis (NEC), a devastating intestinal disease that primarily affects premature and medically fragile babies.
The NEC Biorepository is directed by Dr. Misty Good, a neonatologist at Washington University, with support from Dr. Troy Markel, a pediatric surgeon at Indiana University, and Jennifer Canvasser, the NEC Society’s founder and director.
The following centers have been approved to participate in the NEC Biorepository:
- Washington University in St. Louis – led by Dr. Misty Good
- Indiana University – led by Dr. Troy Markel
- University of Michigan – led by Drs. Samir Gadepalli/Matt Ralls
- Nationwide Children’s Hospital – led by Dr. Gail Besner
- Louisiana State University – led by Dr. Sunyoung Kim
- Baylor/Texas Children’s – led by Dr. Amy Hair
Dr. Good is building a robust biorepository of biological samples from infants affected by NEC. The NEC Biorepository includes samples such as blood, urine, stool, gastric contents, DNA, a breast milk sample (if available), and intestine (if removed) from infants with NEC. The Biorepository also includes specimens from infants that did not develop NEC, yet had intestine removed for other purposes such as a reanastamosis, spontaneous intestinal perforations or volvulus. The development of the NEC Biorepository was featured in Seminars in Pediatric Surgery, as well as the SIGNEC meeting in the UK.
Dr. Good and the NEC Society team believe the NEC Biorepository is essential to advancing the science that will lead to the development of novel diagnostic approaches. Such a breakthrough will enable clinicians to identify therapeutic targets to most effectively prevent and treat the disease. The NEC Biorepository serves as an international resource to provide scientists with the necessary samples to aid in their quest to eliminate NEC. The NEC Biorepository provides an opportunity to facilitate collaborations between multiple centers and expand the available number of patients, biological samples, and corresponding clinical data. The ultimate goal is to develop a biomarker or genetic test to predict a baby’s risk of developing the disease and offer preventive strategies against it. In collaboration with informatic specialists, Dr. Good has developed the clinical and biospecimen databases for the NEC Biorepository to integrate the clinical data and the sample metadata for all of the participating centers.
Please visit the NEC Society’s donate page if you would like to support the NEC Biorepository.
Please email Jennifer@NECsociety.org if you have questions.