Neonatal Probiotics Toolkit

The Toolkit is intended as a resource for clinicians in neonatal intensive care units seeking to gain a better understanding of probiotics use in the NICU. It is not a recommendation for or against the routine use of probiotics in the NICU or for or against the use of any product or preparation.

INTRODUCTION

THE GUT MICROBIOME

The gut microbiome is a collection of all microbes that live in the intestines and provide protection against pathogens, help develop the immune system, and aid in digestion and energy production. The disruption of the gut microbiome, referred to as intestinal dysbiosis, defines an imbalance of the structure and function of this community of microbes. In neonates, several factors may influence the gut microbiome including gestational age (GA), type of feeding, antibiotic exposure, and the maternal microbiome. Continue reading the full publication.

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